Acute Pancreatitis Treatment Market: Introduction
Acute pancreatitis is a sudden inflammation in the pancreas due to various reasons including gallstone, systemic disease, and heavy alcohol use. Usually, gallstones cause about 40% of cases of acute pancreatitis. Mild acute pancreatitis is treated with short-term hospitalization where fluids are given by vein (intravenously), analgesics are administered for pain relief, and nutritional diet. Moderately severe acute pancreatitis requires hospitalization for a longer period of time and patients are given intravenous fluids. In case of severe acute pancreatitis, patients are admitted to the ICU for further treatment.
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Key Drivers and Restraints of Global Acute Pancreatitis Treatment Market
The incidence of acute pancreatitis is increasing worldwide due to an increase in rates of obesity and gallstones. According to WHO, in 2016, 39% of adults aged 18 years and over were overweight. Overall, about 13% of the world’s adult population (11% of men and 15% of women) was obese in 2016. The worldwide prevalence of obesity nearly tripled between 1975 and 2016.
Incidence of acute pancreatitis was reported from 17 countries across Europe and ranged from 4.6 to 100 per 100 000 population. Incidence was usually highest in eastern or northern Europe; however, reported rates often varied according to case ascertainment criteria. Currently, acute pancreatitis is a highly common reason for hospitalization for a gastrointestinal related disease in the U.S.
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However, poor reimbursement policies for the treatment may hamper the market. Acute pancreatitis (AP) is a highly common gastrointestinal cause for hospitalization in the U.S. The estimated total cost for acute pancreatitis admissions was US$ 2.2 billion at a mean cost per hospitalization of US$ 9870, and a mean cost per hospital day of US$ 1670. Poor reimbursement for the treatment procedure may negatively impact lower-middle income countries, which is likely to hamper the market.
Device-based Therapy to Dominate Global Acute Pancreatitis Treatment Market
Based on treatment type, the global acute pancreatitis treatment market can be divided into drug therapy, device based therapy, and others. The drug-based therapy segment can be further segregated into analgesics, antibiotics, and others. The device based-therapy segment can be further classified into intravenous fluid, endoscopic retrograde Cholangiopancreatography (ERCP), and surgery. The others segment can be split into nutritional support, antioxidant therapy, and others.
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The device-based therapy segment dominated the global acute pancreatitis treatment market, in terms of revenue generation, in 2019. Intravenous fluid is the primary treatment for acute pancreatitis, which is done within the first 24 hours of onset. The success rate in performing Endoscopic Retrograde Cholangiopancreatography (ERCP) procedure varies from 70% to 95%, depending on the experience of the physician.
However, the drug therapy segment is estimated to expand at a notable CAGR during the forecast period due to pipeline products and rising investment of pharmaceutical companies. In 2019, the active pain pipeline is populated by 909 products across all stages of development. In 2017, Sanofi launched a topical analgesic, Combiflam Icyhot in the pain-care segment and extended its portfolio.
Hospitals Segment Witness Highest Growth
Based on end-user, the global acute pancreatitis treatment market can be divided into hospitals, ambulatory surgical centers and others
The hospitals segment accounted for a prominent share of the acute pancreatitis treatment market in 2019. It is also estimated to expand at a notable CAGR during the forecast period. Hospitals are always well-equipped with all facilities under one roof, which prompts acute pancreatic patients to visit hospitals for treatment.
Increasing penetration of connected devices and instruments is another factor boosting hospital visits. Gallstone is a major cause of acute pancreatitis. Approximately 20 million people in the U.S. have gallstones. Of these people, there are approximately 300,000 cholecystectomies performed annually.
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North America to Dominate Global Acute Pancreatitis Treatment Market
In terms of region, the global acute pancreatitis treatment market can be divided into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa
In terms of revenue, North America dominated the acute pancreatitis treatment followed by Europe. The reported annual incidence of acute pancreatitis in the U.S. ranges from 4.9 to 35 per 100,000 population.
However, the market in Asia Pacific is estimate to expand at a significant CAGR during the forecast period due to vast patient population, which is rising. Moreover, increasing investment in healthcare in the region further boosts the market. In Japan, the estimated number of patients with AP showed a 1.8-fold increase in the last decade. Based on the survey published in NCBI in 2015, the prevalence in Japan was 49.4 per 100,000 population.
Key Manufacturers Operating in Market
The global acute pancreatitis treatment market was highly fragmented in 2019. Key manufacturers operating in the global market are:
- CalciMedica
- SCM Lifescience
- Samsung Bioepis
- GNT Pharma Co
- AstraZeneca
- Braun Melsungen AG
- General Electric Company
- Medtronic
- Abbott Laboratories
- Sun BioPharma, Inc
- Boston Scientific Corporation
- Fresenius Kabi USA
- GlaxoSmithKline
- Novartis AG
- Pfizer
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